| 19.05.2022 |  | Chelsea - Leicester | x | | | | | x |
| 19.05.2022 | | Everton - Crystal Palace | x | x | | | | |
| 19.05.2022 | | Aston Villa - Burnley | | | | x | | |
| 19.05.2022 |  | Grasshoppers - St.Gallen | | | | | x | x |
| 19.05.2022 | | Luzern - Young Boys | | | x | | x | x |
| 19.05.2022 | | Servette - Basel | | x | x | | x | x |
| 16.05.2022 |  | Juventus - Lazio | x | x | | | x | x |
| 16.05.2022 | | Sampdoria - Fiorentina | | | x | | | |
| 16.05.2022 | | Newcastle - Arsenal | | | x | | | x |
| 16.05.2022 |  | Aalesund - Molde | | x | x | | x | x |
| 16.05.2022 | | Rosenborg - Sandefjord | x | | | | | x |
| 16.05.2022 | | Bodo Glimt - Tromso | x | | | | | |
| 15.05.2022 | | Milan - Atalanta | x | | | | | |
| 15.05.2022 | | Cagliari - Inter | | | x | | | |
| 15.05.2022 | | Bologna - Sassuolo | | | | | x | x |
| 15.05.2022 | | West Ham - Man City | | | x | | | x |
| 15.05.2022 | | Everton - Brentford | x | | | | | |
| 15.05.2022 | | Tottenham - Burnley | x | | | | | x |
| 15.05.2022 |  | Hammarby - AIK | x | x | | | x | |
| 14.05.2022 | | Empoli - Salernitana | | x | x | | | |
| 14.05.2022 | | Verona - Torino | | | | | x | |
| 14.05.2022 | | Roma - Venezia | x | | | | | x |
| 14.05.2022 |  | Leverkusen - Freiburg | x | | | | x | x |
| 14.05.2022 | | Mgladbach - Hoffenheim | | | | | x | x |
| 14.05.2022 | | Mainz - Eintracht | | | | | x | x |
| 14.05.2022 | | Sirius - Elfsborg | | | x | | | x |
| 13.05.2022 |  | Juniors - Kapfenberg | | | | | | x |
| 13.05.2022 | | Linz - Liefering | | | | | x | x |
| 13.05.2022 | | Horn - A.Lustenau | | | | | x | x |
| 13.05.2022 |  | Dundalk - Bohemians | x | x | | | | |
| 13.05.2022 | | Shamrock - Derry City | x | | | | | |
| 12.05.2022 |  | Real Madrid - Levante | | | | | x | x |
| 12.05.2022 | | Real Sociedad - Cadiz | x | | | | | |
| 12.05.2022 | | Rayo Valecano - Villareal | | | x | x | | |
| 12.05.2022 | | Tottenham - Arsenal | | x | x | | x | x |
| 12.05.2022 | | Tromso - Valerenga | | | | | x | |
| 12.05.2022 | | Viking - Stromgodset | x | | | | | |
| 12.05.2022 | | Basel - Grasshoppers | | | | | x | x |
| 11.05.2022 | | Sevilla - Mallorca | x | | | | | |
| 11.05.2022 | | Juventus - Inter | | x | x | | x | |
| 11.05.2022 | | Leeds - Chelsea | | | x | | x | x |
| 11.05.2022 | | Wolves - Man City | | | x | | | |
| 11.05.2022 | | Watford - Everton | | | x | | | |
| 10.05.2022 | | Barcelona - Celta Vigo | x | | | | x | x |
| 10.05.2022 | | Valencia - Betis | | | | | x | |
| 10.05.2022 | | Granada - Athletic Bilbao | | x | x | | | |
| 10.05.2022 | | Aston Villa - Liverpool | | | x | | | x |
| 10.05.2022 | | Kriens - Vaduz | | | x | | | x |
| 10.05.2022 | | Young Boys - St.Gallen | | | | | x | x |
| 09.05.2022 | | Fiorentina - Roma | | x | x | | | x |
| 09.05.2022 | | Elfsborg - Djurgarden | | | | | x | x |
| 09.05.2022 | | Helsingborg - Norrkoping | | x | x | | | |
| 09.05.2022 | | Sandnes - Fredrikstad | | | | | x | x |
| 09.05.2022 | | Skeid - Mjondalen | | | x | | | x |
| 09.05.2022 | | KFUM - Brann | | | x | | | |
| 08.05.2022 | | Man City - Newcastle | x | | | | | x |
| 08.05.2022 | | Arsenal - Leeds | x | | | | | x |
| 08.05.2022 | | Norwich - West Ham | | | x | | | x |
| 08.05.2022 | | Verona - Milan | | | x | | | |
| 08.05.2022 | | Spezia - Atalanta | | | x | | | x |
| 08.05.2022 | | Atletico Madrid - Real Madrid | | | | | x | |
| 08.05.2022 | | Eintracht - Mgladbach | | | | | x | x |
| 08.05.2022 | | Bayern M - Stuttgart | | | | | x | x |
| 07.05.2022 | | Liverpool - Tottenham | x | | | | x | x |
| 07.05.2022 | | Chelsea - Wolves | x | | | | | |
| 07.05.2022 | | Torino - Napoli | | x | x | | | |
| 07.05.2022 | | Lazio - Sampdoria | x | | | | x | x |
| 07.05.2022 | | Greuther - Dortmund | | | x | | | x |
| 07.05.2022 | | Hoffenheim - Leverkusen | | | | | x | x |
| 06.05.2022 | | Inter - Empoli | x | | | | | x |
| 06.05.2022 | | Genoa - Juventus | | x | x | | | |
| 06.05.2022 | | Levante - Real Sociedad | | x | x | | | |
| 06.05.2022 | | Paderborn - Sandhausen | x | | | | | x |
| 06.05.2022 | | Fortuna - Darmstadt | | x | x | | | |
| 05.05.2022 | | Djurgarden - Helsingborg | x | | | | | x |
| 05.05.2022 | | Salernitana - Venezia | | | | | x | x |
| 05.05.2022 | Europa League | Eintracht - West Ham | | | | | x | |
| 05.05.2022 | Europa League | Rangers - Leipzig | | | x | | | |
| 05.05.2022 | Europa League Conference | Marseille - Feyenoord | x | x | | | x | x |
| 05.05.2022 | Europa League Conference | Roma - Leicester | x | x | | | x | |
